What Are The Side Effects Of Vitamin E?

The basic concept of vitamin E

Vitamin E is a fat-soluble vitamin. It is found in vegetable oils, dices, meat, poultry, eggs, fruits, vegetables, and wheat germ oil, and can also be obtained through nutritional supplements.

Do you want to know what are the side effects of vitamin e?

Vitamin E can be used to:

Treatment of Vitamin E Deficiency: Although vitamin E deficiency is rare, some people with genetic defects and premature infants with very low weight may have this condition.

  • Treatment and prevention of cardiovascular diseases: including arteriosclerosis, Heart Disease, chest pain, leg pain due to blocked arteries, Hypertension, treatment of Diabete, and its complications.
  • Prevention of Cancer: Especially lung cancer and oral cancer, colorectal cancer and polyps, stomach cancer, prostate cancer, and pancreatic cancer of smokers.
  • Treats Huntington’s chorea and other nerve and muscle-related defects.
  • Treatment of Cataracts, Asthma, respiratory infections, skin diseases, skin aging, sunburn, cystic fibrosis, infertility, impotence, chronic fatigue syndrome, peptic ulcers, certain specific genetic diseases, and prevention of allergies.
  • To reduce the harmful effects caused by hemodialysis and radiotherapy, it is also used to reduce the side effects of hair loss in patients using Doxorubicin and lung damage in patients using Amiodarone.
  • Combined with other drugs and used in brain and nervous system diseases: including Alzheimer`s Disease, Alzheimer’s disease, Parkinson’s disease, night cramps, restless leg syndrome (Restless Leg Syndrome, also known as leg restless syndrome), and epilepsy, etc.
  • Women can use vitamin E to prevent complications caused by high blood pressure in late pregnancy, including preeclampsia (pregnancy toxemia), premenstrual syndrome (PMS), menstrual pain, menopausal syndrome, breast cancer-related hot flashes, and breast cysts.

Vitamin E is also used to improve physical endurance, increase energy, reduce muscle damage after exercise, and improve muscle strength.

Some people also use vitamin E on their skin to slow down aging and protect the skin from chemotherapy.

The principle of vitamin E

At present, there is not enough research to show the efficacy of vitamin E. If you need further information, please discuss it with your doctor or herbalist.

However, it is now known that vitamin E is an important vitamin that allows many organs of the body to function normally.

It is also Antioxidant. In other words, vitamin E helps slow down the process of cell damage.

Precautions of vitamin E

If you encounter the following conditions, please consult a physician, pharmacist, or herbalist to determine whether vitamin E is suitable:

  • During pregnancy or breastfeeding.
  • Are taking other medicines.
  • Allergy to vitamin E ingredients, other medicines, or other herbs.
  • Suffering from other diseases, illnesses, or physical conditions.
  • There are other allergic symptoms, such as allergies to food, dyes, preservatives, or animals.

Compared with the regulation of medicines, the regulation of herbal medicines is less strict, and more research is needed to prove its safety.

Before use, please make sure that the benefits outweigh the risks. It is recommended to consult an herbalist or physician for more information.

Is it safe to use vitamin E?

Oral or topical vitamin E is safe for most people. Most people do not produce any side effects when using the recommended daily dosage of 15 mg.

If you take too much vitamin E by mouth, it may be unsafe, especially if you have heart disease or diabetes. Do not use more than 400 international units of vitamin E a day.

Some studies have pointed out that high doses of vitamin E may increase the chance of death and cause other serious side effects.

The higher the dose, the higher the risk of serious side effects.

Vitamin E increases the risk of hemorrhagic stroke caused by intracerebral hemorrhage.

Some studies have shown that daily use of 300 to 800 international units of vitamin E may increase the chance of a hemorrhagic stroke by up to 22%.

Conversely, vitamin E may reduce the chance of ischemic stroke (Ischemic Stroke), which is a relatively minor type of stroke.

There are also different findings regarding vitamin E for the development of prostate cancer.

Some studies have pointed out that the use of large amounts of multivitamins plus vitamin E may increase the chance of some men suffering from prostate cancer.

Special attention items


When the dosage is within the recommended daily dosage, vitamin E should be safe for pregnant women.

Although there are still doubts about whether the use of vitamin E nutritional supplements in early pregnancy will harm the fetus, but whether such doubts have a significant impact can not be concluded too quickly.

Therefore, before there is more information, please do not use vitamin E nutritional supplements in the early pregnancy without the instructions of medical care personnel.


It is safe to use the recommended amount of oral vitamin E during breastfeeding.

Infants and children

It is generally safe to take vitamin E in moderation, and the safe use of vitamin E varies with age.

  • Intravenous high-dose vitamin E may not be safe for infants
  • The recommended daily dosage for children 1 to 3 years old is not more than 200 mg
  • The recommended daily dosage for children aged 4-8 years is not more than 300 mg
  • The recommended daily dosage for children 9 to 13 years old does not exceed 600 mg
  • The recommended daily dosage for adolescents between 14 and 18 years old does not exceed 800 mg


Avoid using vitamin E or other antioxidant vitamins (such as beta-carotene, vitamin C) without monitoring by medical professionals. Such vitamins may interfere with wound healing.


Vitamin E may increase the risk of heart failure in diabetes, so people with diabetes should avoid using high doses of vitamin E.

Heart disease

Vitamin E may increase the risk of death in patients with heart disease, so patients with heart disease should avoid using high doses of vitamin E.

Vitamin K deficiency

Vitamin E may worsen blood clotting problems in patients with too low vitamin K.

Retinitis pigmentosa: 400 international units of vitamin E accelerates the loss of vision in patients with retinitis pigmentosa.

However, using very small amounts of vitamin E (less than 3 IU) does not seem to cause this result, so if you have retinitis pigmentosa, it is best to avoid using vitamin E.

Bleeding defects

Vitamin E may worsen bleeding defects. If you have bleeding defects, avoid using vitamin E nutritional supplements.

Head and neck cancer

Do not use more than 400 international units of vitamin E daily, because excessive amounts will increase the chance of cancer recurrence.

Prostate cancer

The use of vitamin E can increase the chance of prostate cancer. The effect of vitamin E on men with prostate cancer is still unknown.

However, in theory, the use of vitamin E nutritional supplements may worsen the condition of men who already have prostate cancer.


Vitamin E may increase the risk of death in patients with a history of stroke. Patients with a history of stroke should avoid high doses of vitamin E.


Vitamin E may increase the risk of bleeding during and after surgery. Vitamin E should be stopped at least two weeks before the scheduled surgery.

What are the side effects of Vitamin E?

Using high doses of vitamin E may cause side effects such as nausea, diarrhea, stomach cramps, fatigue, weakness, headache, blurred vision, rash, bruising, and bleeding.

Not everyone will experience these side effects, and some side effects may not be listed. If you have any concerns about side effects, please consult your physician.

Potential interactions with vitamin E

Vitamin E may interact with your current medication or condition. Consult a physician before use.

Products that interact with vitamin E include:


The simultaneous use of a large amount of vitamin E and cyclosporine may increase the amount of cyclosporine absorbed by the human body; the amount of cyclosporine absorbed will increase, and its effects and side effects may also increase.

Drugs that can be changed by the liver

Vitamin E may accelerate the rate at which the liver breaks down certain drugs.

Simultaneous use of vitamin E and certain drugs that can be broken down by the liver can reduce the effectiveness of the drug.

Drugs that can be affected by the liver include Lovastatin, Ketoconazole, Itraconazole, Fexofenadine, Triazolam, and other drugs.

Cancer treatment drugs (chemotherapy)

Vitamin E is an antioxidant, so it may reduce the effectiveness of cancer drugs, but whether such interaction studies exist still cannot be confirmed.

Drugs that slow blood clotting (Anticoagulant / Antiplatelet drugs)

Simultaneous use of vitamin E and drugs that slow blood clotting may increase the chance of bruising and bleeding; drugs that slow blood clotting include aspirin, Baoshuantong, Diclofenac, Ibuprofen, Naproxen, Dalteparin, Heparin, Warfarin, etc.

Cholesterol-lowering drugs (Statins)

Simultaneous use of vitamin E, β-carotene, vitamin C, and Selenium may reduce the effectiveness of certain cholesterol-lowering drugs. Cholesterol-lowering drugs include Atorvastatin, Fluvastatin, lovastatin, and Pravastatin.


Simultaneous use of vitamin E, beta-carotene, vitamin C, and selenium may reduce the benefits of niacin and increase good cholesterol levels.

The recommended dosage of vitamin E

The following information is not a medical diagnosis, please consult a physician or herbalist before using. What is the general usage of vitamin E?


  • Insufficient vitamin E: Adults generally need to use 60 to 75 international units per day.
  • Patients with delayed-onset exercise: a daily recommended dosage of 1600 international units.
  • Improve male infertility: 200~600 international units per day.
  • Alzheimer’s disease: Use up to 2000 international units of vitamin E daily. At present, 5 mg of Donepezil and 1000 IU of vitamin E are commonly used daily to slow down the memory decline in patients with Alzheimer’s disease.
  • Non-alcoholic steatohepatitis: Adults use 800 international units per day; children use 400 to 1200 international units per day.
  • Early Huntington’s disease: 3000 international units of RRR-α-tocopherol (one of the natural forms of vitamin E).
  • Pain caused by rheumatoid arthritis: 600 IU vitamin E, 2 times a day.
  • Prevention of nerve damage caused by Cisplatin: 300 mg of vitamin E (α-tocopherol) is used daily during chemotherapy, and the use of vitamin E is continued for up to three months after stopping cisplatin treatment.
  • Improve the effect of nitrite for heart disease: use 200 mg of vitamin E 3 times a day.
  • Reduce proteinuria symptoms in children with partial glomerulosclerosis: 200 IU of vitamin E.
  • Glucose-6-phosphate dehydrogenase deficiency (commonly known as broad bean disease): 800 international units of vitamin E per day.
  • Premenstrual syndrome: RRR-α-tocopherol (natural vitamin E) 400 international units per day.
  • Menstrual cramps: use vitamin E twice a day, 200 IU, or once a day, 500 IU each time; start using it two days before menstruation, and continue to use it for the first 3 days.
  • Healing keratotomy: use 230 mg of vitamin E (a new inducer of α-tocopherol) and 25,000 units of vitamin A (especially vitamin A palmitate) 3 times a day for 30 days, then every 2 times a day for 2 months.
  • Fibrosis due to radiation: 1000 International Units of Vitamin E per day, with 800 mg of Pertoxiline.
  • Thalassemia B: 750 international units of vitamin E daily.
  • Pre-sun protection: RRR-α-tocopherol (natural vitamin E) 1000 international units, with 2 grams of ascorbic acid (vitamin C).
  • Prevention of high-risk women’s pregnancy-induced hypertension (pregnant toxemia): Vitamin E 400 international units daily, with vitamin C 1000 mg.

The recommended dosage of vitamin E sometimes makes people unsure of the situation.

The daily recommended amount and upper limit of intake in the instructions for use are now marked in milligrams, but most products are still marked in international units.

The amount of vitamin E varies from person to person, mainly affected by age, health, and other diseases; and this type of herbal supplement is not necessarily safe.

Therefore, please consult your physician or herbalist to know the dosage suitable for you before taking it.

Types of finished products of vitamin E

Vitamin E can be obtained in the following forms:

  • Naturally exists in certain foods
  • Soft capsule
  • capsule

Where can I the Vitamin E?

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Vitamin E

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